Ethanolamine → 4-[4-(4-Fluoro-phenyl)-piperidin-1-yl]-2-(2-hydroxy-ethylamino)-6-(2,2,2-trifluoro-ethoxy)-pyrimidine-5-carbonitrile

Reaktionsgleichung

[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[CH2:13][CH2:12][N:11]([C:14]3[C:19]([C:20]#[N:21])=[C:18]([O:22][CH2:23][C:24]([F:27])([F:26])[F:25])[N:17]=[C:16](SC)[N:15]=3)[CH2:10][CH2:9]2)=[CH:4][CH:3]=1.ClC1C=CC=C(C(OO)=O)C=1.FC1C=CC(C2CCN(C3C(C#N)=C(OCC(F)(F)F)N=C(S(C)(=O)=O)N=3)CC2)=CC=1.[CH2:72]([CH2:74][NH2:75])[OH:73]>O1CCOCC1>[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[CH2:13][CH2:12][N:11]([C:14]3[C:19]([C:20]#[N:21])=[C:18]([O:22][CH2:23][C:24]([F:27])([F:26])[F:25])[N:17]=[C:16]([NH:75][CH2:74][CH2:72][OH:73])[N:15]=3)[CH2:10][CH2:9]2)=[CH:4][CH:3]=1