N-(1-Phenethyl-piperidin-3-ylmethyl)-N-phenyl-propionamide → (S)N-(1-Phenethyl-piperidin-3-ylmethyl)-N-phenyl-propionamide

HRID 1839197Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1839197
C(N1CCC[C@@H](CN(C2C=CC=CC=2)C(=O)CC)C1)(OC(C)(C)C)=O.[CH2:26]([N:34]1[CH2:39][CH2:38][CH2:37][CH:36]([CH2:40][N:41]([C:46]2[CH:51]=[CH:50][CH:49]=[CH:48][CH:47]=2)[C:42](=[O:45])[CH2:43][CH3:44])[CH2:35]1)[CH2:27][C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1>>[CH2:26]([N:34]1[CH2:39][CH2:38][CH2:37][C@H:36]([CH2:40][N:41]([C:46]2[CH:51]=[CH:50][CH:49]=[CH:48][CH:47]=2)[C:42](=[O:45])[CH2:43][CH3:44])[CH2:35]1)[CH2:27][C:28]1[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=1

Komponenten

3

Edukt 2

HCID 9950309N-(1-Phenethyl-piperidin-3-ylmethyl)-N-phenyl-propionamideHCID 20598049(S)-N-(1-Boc-piperidin-3-ylmethyl)-N-phenyl-propionamide

Produkt 1

HCID 20611323(S)N-(1-Phenethyl-piperidin-3-ylmethyl)-N-phenyl-propionamide

Versuchsvorschrift

Following the procedures described in Example 5, (S)-N-(1-Boc-piperidin-3-ylmethyl)-N-phenyl-propionamide 31 was converted to (S) N-(1-Phenethyl-piperidin-3-ylmethyl)-N-phenyl-propionamide 32 (LRMS 350).

Quellen und Nachweise

ORD-Eintrag
ord-337cfeb46011445685e937b7fbdea8a1
Quelldatensatz
uspto-grants-2004_01
Patentnummer
US06677332B1

Notizen zur Reaktion

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