(Chloromethyl)cyclohexane → 5,6-bis(4-methoxyphenyl)-4-cyano-2-cyclohexylmethyl-2H-pyridazin-3-one
Reaktionsgleichung
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:14]([C:15]3[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=3)=[N:13][NH:12][C:11](=[O:23])[C:10]=2[C:24]#[N:25])=[CH:5][CH:4]=1.[CH:26]1([CH2:32]Cl)[CH2:31][CH2:30][CH2:29][CH2:28][CH2:27]1>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:14]([C:15]3[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=3)=[N:13][N:12]([CH2:32][CH:26]3[CH2:31][CH2:30][CH2:29][CH2:28][CH2:27]3)[C:11](=[O:23])[C:10]=2[C:24]#[N:25])=[CH:5][CH:4]=1Komponenten
3
Versuchsvorschrift
Using 5,6-bis(4-methoxyphenyl)-4-cyano-2H-pyridazin-3-one and cyclohexylmethyl chloride as starting materials, the procedures of Example 1 were repeated likewise, whereby the title compound was obtained in a yield of 45.0%.
Quellen und Nachweise
- ORD-Eintrag
- ord-95353cb5f6e345f591e97dc3b54b745d
- Quelldatensatz
- uspto-grants-2004_01