Benzyl Chloride → 2-Benzyl-5,6-bis(4-methoxyphenyl)-4-cyano-2H-pyridazin-3-one
Reaktionsgleichung
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:14]([C:15]3[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=3)=[N:13][NH:12][C:11](=[O:23])[C:10]=2[C:24]#[N:25])=[CH:5][CH:4]=1.[CH2:26](Cl)[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1>>[CH2:26]([N:12]1[C:11](=[O:23])[C:10]([C:24]#[N:25])=[C:9]([C:6]2[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)[C:14]([C:15]2[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=2)=[N:13]1)[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1Komponenten
3
Versuchsvorschrift
Using 5,6-bis(4-methoxyphenyl)-4-cyano-2H-pyridazin-3-one and benzyl chloride as starting materials, the procedures of Example 1 were repeated likewise, whereby the title compound was obtained in a yield of 65.4%.
Quellen und Nachweise
- ORD-Eintrag
- ord-415c193fe155431a960fe113f6c10ad7
- Quelldatensatz
- uspto-grants-2004_01