6-Acetyl-1-heptyl-4,4-dimethyl-3,4-dihydroquinolin-2(1H)-one → HCID 69038572, Verbindung
Reaktionsgleichung
[CH2:1]([N:7]1[C:16]2[C:11](=[CH:12][C:13]([C:17](=[O:29])[CH:18]=[CH:19][C:20]3[CH:28]=[CH:27][C:23]([C:24]([OH:26])=[O:25])=[CH:22][CH:21]=3)=[CH:14][CH:15]=2)[C:10]([CH3:31])([CH3:30])[CH2:9][C:8]1=[O:32])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].[CH2:33](N1C2C(=CC(C(=O)C)=CC=2)C(C)(C)CC1=O)CCCCCC>>[CH2:1]([N:7]1[C:16]2[C:11](=[CH:12][C:13]([C:17](=[O:29])[CH:18]=[CH:19][C:20]3[CH:28]=[CH:27][C:23]([C:24]([OH:26])=[O:25])=[CH:22][CH:21]=3)=[CH:14][CH:15]=2)[C:10]([CH3:31])([CH3:30])[CH2:9][C:8]1=[O:32])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:33]Komponenten
3
Versuchsvorschrift
Following a procedure similar to that used for the preparation of Compound 8a but using N-heptyl-6-acetyl-4,4-dimethyl-3,4-dihydro-1H-quinolin-2-one (Intermediate 6b) as the starting material afforded the title compound as a light yellow solid (51% yield).
Quellen und Nachweise
- ORD-Eintrag
- ord-59c8caff42c54e818d890543ceea4f35
- Quelldatensatz
- uspto-grants-2004_01