3,4-Dichlorocinnamic acid → (R)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-[E-3-(3,4-dichlorophenyl)propenamide]

Beteiligte Stoffe

Reaktionsschritte

Prepared as a free base by a method analogous to that described in Example 1 from (R)-1-azabicyclo[2.2.2]oct-3-ylamine dihydrochloride and E-3-(3,4-dichlorophenyl)propenoic acid; the compound was purified by chromatography on silica gel using ammoniated methanol/chloroform mixtures as the eluent; MS (ES+) 325, 327, 329 (MH+).

Herkunft & Nachweise