3-(difluoromethyl)-1-methyl-4-(trifluoromethyl)-1H-pyrazole-5-carboxylic acid → 3-[cyclopropyl(hydroxy)methyl]-1-methyl-4-(trifluoromethyl)-1H-pyrazole-5-carboxylic acid

HRID 1843101Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1843101
FC(F)C1C(C(F)(F)F)=C(C(O)=O)N(C)N=1.[CH:17]1([CH:20]([OH:36])[C:21]2[C:25]([C:26]([F:29])([F:28])[F:27])=[C:24]([C:30]([O:32]CC)=[O:31])[N:23]([CH3:35])[N:22]=2)[CH2:19][CH2:18]1>>[CH:17]1([CH:20]([OH:36])[C:21]2[C:25]([C:26]([F:28])([F:29])[F:27])=[C:24]([C:30]([OH:32])=[O:31])[N:23]([CH3:35])[N:22]=2)[CH2:19][CH2:18]1

Komponenten

3

Edukt 2

HCID 585425153-(difluoromethyl)-1-methyl-4-(trifluoromethyl)-1H-pyrazole-5-carboxylic acidHCID 58542559ethyl 3-[cyclopropyl(hydroxy)methyl]-1-methyl-4-(trifluoromethyl)-1H-pyrazole-5-carboxylate

Produkt 1

HCID 585425253-[cyclopropyl(hydroxy)methyl]-1-methyl-4-(trifluoromethyl)-1H-pyrazole-5-carboxylic acid

Versuchsvorschrift

This compound is prepared analogously to the preparation of 3-(difluoromethyl)-1-methyl-4-(trifluoromethyl)-1H-pyrazole-5-carboxylic acid from ethyl 3-[cyclopropyl(hydroxy)methyl]-1-methyl-4-(trifluoromethyl)-1H-pyrazole-5-carboxylate.

Quellen und Nachweise

ORD-Eintrag
ord-ec18bfe4f7334e24804f024f97a052be
Quelldatensatz
uspto-grants-2015_02
Patentnummer
US08946234B2

Notizen zur Reaktion

Wird geladen…