HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-(3-Fluorophenyl)-2-propenoic acid → 3-(3-Fluorophenyl)propionic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-(3-Fluorophenyl)-2-propenoic acid | HCID 88606 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | 3-(3-Fluorophenyl)propionic acid | HCID 2737489 | 80,69% |
Reaktionsschritte
3-(3-Fluorophenyl)acrylic acid (I-78a: 6.4 gm, 38.5 mmol) in methanol (100 mL) was reduced with 10% Pd/C (640 mg) to afford the crude product, 5 g (80.69% yield).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08946260B2 |
| Quelldatensatz | uspto-grants-2015_02 |
| ORD ID | ord-7a510fce0be64052bf67aa17848ce7a5 |
| Quellennotiz | uspto-grants-2015_02 |