Acrolein dimer → [(1-Cyclopentyl-1H-tetrazol-5-yl)-(3,4-dihydro-2H-pyran-2-yl)-methyl]-(3-imidazol-1-yl-propyl)-amine

Beteiligte Stoffe

Reaktionsschritte

3-Imidazol-1-yl-propylamine (1 mmol) and 3,4-Dihydro-2H-pyran-2-carbaldehyde (1 mmol) were combined in methanol (2 ml, dry). After 2 hours Trimethylsilylazide (5 mmol) and Isocyano-cyclopentan (1 mmol) was added. The reaction was stirred at room temperature for 48 h. After evaporation of the solvent the residue was purified with chromatographic methods.

Herkunft & Nachweise