(1S,3R)-3-aminocyclohexanecarboxylic acid trifluoroacetate → ((1S,3R)-3-Aminocyclohexyl)methanol

HRID 1848226

Reaktionsgleichung

Reaktionsgleichung von HRID 1848226
FC(F)(F)C(O)=O.[NH2:8][C@@H:9]1[CH2:14][CH2:13][CH2:12][C@H:11]([C:15](O)=[O:16])[CH2:10]1.Cl.N[C@H]1CC[C@H](C(O)=O)CC1>>[NH2:8][C@@H:9]1[CH2:14][CH2:13][CH2:12][C@H:11]([CH2:15][OH:16])[CH2:10]1

Komponenten

3

Edukt 2

HCID 86681199(1S,3R)-3-aminocyclohexanecarboxylic acid trifluoroacetateHCID 178479263HCID 178479263, Verbindung

Produkt 1

HCID 67278447((1S,3R)-3-Aminocyclohexyl)methanol

Versuchsvorschrift

((1S,3R)-3-Aminocyclohexyl)methanol was synthesized as a white powder (157 mg, 59%) using a procedure analogous to that described in Step 1 of Example 179, substituting (1S,3R)-3-aminocyclohexanecarboxylic acid trifluoroacetate from the previous step for trans-4-aminocyclohexanecarboxylic acid hydrochloride used in Example 179.

Quellen und Nachweise

ORD-Eintrag
ord-98961ae179194e2db9d4eb682848f381
Quelldatensatz
uspto-grants-2015_02
Patentnummer
US08952058B2

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