HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Hydroxybenzaldehyde → 3-(Dimethylaminomethyl)phenol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Hydroxybenzaldehyde | HCID 101 | — |
| Edukt | Dimethylamine | HCID 674 | — |
| Edukt | Methanol | HCID 887 | — |
| Edukt | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | 3-(Dimethylaminomethyl)phenol | HCID 32896 | — |
Reaktionsschritte
3-Hydroxybenzaldehyde (1.0 g), 2M dimethylamine in THF (5 mL), and sodium triacetoxyborohydride (2 g) in CH2Cl2 (10 mL) were stirred for 24 hours. The mixture was treated with methanol and chromatographed on silica gel with 2-25% ethyl acetate/hexanes.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08952157B2 |
| Quelldatensatz | uspto-grants-2015_02 |
| ORD ID | ord-df5af0ca9d194e2f9c958e27b101116e |
| Quellennotiz | uspto-grants-2015_02 |