Methanol → [4-Acetyloxy-5-[5-fluoro-2-oxo-4-(3,7,11,15-tetramethylhexadecoxycarbonylamino)pyrimidin-1-yl]-2-methyloxolan-3-yl] acetate

HRID 185183Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 185183
[C:1]([CH3:2])(=[O:3])[O:4][CH:5]1[CH:6]([n:15]2[c:16](=[O:17])[n:18][c:19]([NH2:20])[c:21]([F:23])[cH:22]2)[O:7][CH:8]([CH3:14])[CH:9]1[O:10][C:11]([CH3:12])=[O:13].[CH3:48][OH:49].[Cl:24][C:25](=[O:26])[O:27][CH2:28][CH2:29][CH:30]([CH2:31][CH2:32][CH2:33][CH:34]([CH2:35][CH2:36][CH2:37][CH:38]([CH2:39][CH2:40][CH2:41][CH:42]([CH3:43])[CH3:44])[CH3:45])[CH3:46])[CH3:47].[Cl:50][CH2:51][Cl:52].[cH:53]1[cH:54][cH:55][n:56][cH:57][cH:58]1>>[C:1]([CH3:2])(=[O:3])[O:4][CH:5]1[CH:6]([n:15]2[c:16](=[O:17])[n:18][c:19]([NH:20][C:25](=[O:26])[O:27][CH2:28][CH2:29][CH:30]([CH2:31][CH2:32][CH2:33][CH:34]([CH2:35][CH2:36][CH2:37][CH:38]([CH2:39][CH2:40][CH2:41][CH:42]([CH3:43])[CH3:44])[CH3:45])[CH3:46])[CH3:47])[c:21]([F:23])[cH:22]2)[O:7][CH:8]([CH3:14])[CH:9]1[O:10][C:11]([CH3:12])=[O:13]

Komponenten

6

Edukt 5

HCID 887MethanolHCID 1049PyridineHCID 6344DichloromethaneHCID 190026202',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidineHCID 585385033,7,11,15-Tetramethyl-hexadecyl chloroformate

Produkt 1

HCID 70877261[4-Acetyloxy-5-[5-fluoro-2-oxo-4-(3,7,11,15-tetramethylhexadecoxycarbonylamino)pyrimidin-1-yl]-2-methyloxolan-3-yl] acetate

Quellen und Nachweise

ORD-Eintrag
ord-194dbedc2d5e463b997bdc6f1b68f16a
Quelldatensatz
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

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