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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1853259Erstellt: 25. Oktober 2026

Methyl 2-acetamidoacrylate → Methyl 6-methylisoquinoline-3-carboxylate

https://huagongshe.com/reaction/1853259

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktMethyl 2-acetamidoacrylateHCID 98644—
Edukt2-Bromo-4-methylbenzaldehydeHCID 4645292—
ProduktMethyl 6-methylisoquinoline-3-carboxylateHCID 2224364450%

Reaktionsschritte

methyl 6-methyl-isoquinoline-3-carboxylate was prepared using the procedure described in example 12A: 2-bromo-4-methylbenzaldehyde was reacted with methyl 2-acetamidoacrylate at 110° C. for 18 hours to yield methyl 6-methyl-isoquinoline-3-carboxylate (50%) as brown solid.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08962627B2
Quelldatensatzuspto-grants-2015_02
ORD IDord-ed8c84d3d8f7478eac387d95047051c1
Quellennotizuspto-grants-2015_02