Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Water | HCID 962 | — |
| Edukt | Uracil | HCID 1174 | — |
| Edukt | p-Fluoronitrobenzene | HCID 9590 | — |
| Edukt | Cesium carbonate | HCID 10796 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | 1-(4-Nitrophenyl)pyrimidine-2,4-dione | HCID 11276338 | — |
Reaktionsschritte
A mixture of 3.5 g 1H-Pyrimidine-2,4-dione and 3 g 1-Fluoro-4-nitro-benzene and 13.8 g Cs2CO3 in 60 mL DMF was heated to 80° C. for 12 h. This solution was poured on to 200 mL of water and the resulting precipitate was collected by filtration to yield a bright yellow crystalline product, which was dried under reduced pressure. Yield: 2.6 g.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US07741341B2 |
|---|
| Quelldatensatz | uspto-grants-2010_06 |
|---|
| ORD ID | ord-d6ab52a054f44054930b84bdf35417b4 |
|---|
| Quellennotiz | uspto-grants-2010_06 |
|---|
