HCID 689541, Verbindung → HCID 49872914, Verbindung
Reaktionsgleichung
[C:1]12([CH2:11][C:12](Cl)=[O:13])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.[NH2:15][N:16]1[C:21](=[O:22])[C:20]2[CH:23]=[C:24]([CH3:26])[S:25][C:19]=2[N:18]=[C:17]1[CH3:27]>>[C:1]12([CH2:11][C:12]([NH:15][N:16]3[C:21](=[O:22])[C:20]4[CH:23]=[C:24]([CH3:26])[S:25][C:19]=4[N:18]=[C:17]3[CH3:27])=[O:13])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2Komponenten
3
Versuchsvorschrift
1-Adamantaneacetyl chloride and 3-amino-2,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one (Matrix) were processed using the method described in Example 42C to afford the title compound. 1H NMR (300 MHz, DMSO-d6) δ ppm 1.54-1.76 (m, 12 H) 1.89-1.99 (m, 3 H) 2.04-2.18 (m, 2 H) 2.37 (s, 3 H) 2.5 (s, 3 H) 7.09 (s, 1 H) 10.83 (s, 1 H); MS (ESI+) m/z 372 (M+H)+.
Quellen und Nachweise
- ORD-Eintrag
- ord-6a3b607027f84d229f4017a5576054db
- Quelldatensatz
- uspto-grants-2015_02