HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Butane-1,3-dione, 4,4,4-trifluoro-1-(4-imidazol-1-ylphenyl)- → [4-(4-Imidazol-1-yl-phenyl)-6-trifluoromethyl-pyrimidin-2-yl]-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Butane-1,3-dione, 4,4,4-trifluoro-1-(4-imidazol-1-ylphenyl)- | HCID 6426099 | — |
| Edukt | HCID 178493228 | HCID 178493228 | — |
| Produkt | [4-(4-Imidazol-1-yl-phenyl)-6-trifluoromethyl-pyrimidin-2-yl]-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-amine | HCID 57829846 | — |
Reaktionsschritte
The title compound was prepared from 4,4,4-trifluoro-1-(4-imidazol-1-yl-phenyl)-butane-1,3-dione (137 mg, 0.49 mmol) and N-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-guanidine dinitrate (180 mg, 0.49 mmol) using in analogous manner the procedure described in example 29). Obtained as a pale-yellow solid (19 mg, 8%). Mp 248-250° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08962834B2 |
| Quelldatensatz | uspto-grants-2015_02 |
| ORD ID | ord-c21caeb6f91f4d6abb9eb3cfbd5c69de |
| Quellennotiz | uspto-grants-2015_02 |