Ethanol → 2-Ethoxy-5-nitropyridine

HRID 1856714Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1856714
Cl[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][N:3]=1.[OH-].[K+].[CH2:13]([OH:15])[CH3:14]>[Cl-].[NH4+]>[CH2:13]([O:15][C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][N:3]=1)[CH3:14]

Komponenten

5

Edukt 3

HCID 702EthanolHCID 14797Potassium HydroxideHCID 783082-Chloro-5-nitropyridine

Produkt 1

HCID 2958642-Ethoxy-5-nitropyridine

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 25517Ammonium ChlorideLösungsmittel

Versuchsvorschrift

2-Chloro-5-nitropyridine was added to a homogeneous solution of potassium hydroxide (3.93 g, 70 mmol) in ethanol (35 mL) at ambient temperature. The reaction mixture was stirred for 1 h, then diluted with saturated aqueous ammonium chloride and cooled in an ice bath. The precipitate was collected, rinsed with water and dried to give 3.60 g of 2-ethoxy-5-nitropyridine as a beige solid.

Aufarbeitung

  1. temperaturecooled in an ice bath
  2. customThe precipitate was collected
  3. washrinsed with water
  4. customdried

Quellen und Nachweise

ORD-Eintrag
ord-c50769b083d64a799d865218d9a973d3
Quelldatensatz
uspto-grants-2000_11
Patentnummer
US06143760

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