2-Ethoxy-5-nitropyridine → 6-Ethoxypyridin-3-amine

Beteiligte Stoffe

Reaktionsschritte

A mixture of 2-ethoxy-5-nitropyridine (3.60 g) and 10% Pd/C (360 mg) in ethanol (40 mL) was placed in a Paar bottle and shaken under hydrogen (50 PSI) for 16 h. The mixture was filtered through Celite using dichloromethane and concentrated to give 2.892 g of 2-ethoxy-5-aminopyridine as a gold solid.

Herkunft & Nachweise