HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Amino-4-methoxybenzanilide → 3-(2,4-Difluoro-benzenesulfonylamino)-4-methoxy-N-phenyl-benzamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Amino-4-methoxybenzanilide | HCID 8426 | — |
| Edukt | 2,4-Difluorobenzenesulfonyl Chloride | HCID 2734273 | — |
| Lösungsmittel | Pyridine | HCID 1049 | — |
| Produkt | 3-(2,4-Difluoro-benzenesulfonylamino)-4-methoxy-N-phenyl-benzamide | HCID 18626262 | 84,4% |
Reaktionsschritte
Prepared according to the procedure described for Example 121 using 2,4-difluorobenzenesulfonyl chloride (2.19 g, 10 mmol), 3-amino-4-methoxy-N-phenyl-benzamide (2.43 g, 10 mmol), and pyridine (25 mL) to afford the product (3.532 g); m.p. 198-200° C. after trituration in hexanes/ethyl acetate (1:1).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06528528B2 |
| Quelldatensatz | uspto-grants-2003_03 |
| ORD ID | ord-8e0a43a66efd4394b446b0f70e7fd65c |
| Quellennotiz | uspto-grants-2003_03 |