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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1860052Erstellt: 25. Oktober 2026

Sodium Hydroxide → 2-(5-(Trifluoromethyl)pyridin-2-yl)benzoic acid

https://huagongshe.com/reaction/1860052

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktSodium HydroxideHCID 14798—
EduktMethyl 3-trifluoromethylpyridine-6-ylbenzoateHCID 18625897—
Produkt2-(5-(Trifluoromethyl)pyridin-2-yl)benzoic acidHCID 2273690972,7%

Reaktionsschritte

In a similar manner to that described in Example 2, a reaction was carried out using methyl 3-trifluoromethylpyridine-6-ylbenzoate (791 mg) and aqueous sodium hydroxide solution (1N, 5.60 ml) and the reaction mixture was treated to afford the title compound (546 mg) which includes some impurity and was used in example 106 without further purification.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06528525B1
Quelldatensatzuspto-grants-2003_03
ORD IDord-c54feab767b34f7c8e3d3a9cfdd867f1
Quellennotizuspto-grants-2003_03