HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Sodium Hydroxide → 2-(5-(Trifluoromethyl)pyridin-2-yl)benzoic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Sodium Hydroxide | HCID 14798 | — |
| Edukt | Methyl 3-trifluoromethylpyridine-6-ylbenzoate | HCID 18625897 | — |
| Produkt | 2-(5-(Trifluoromethyl)pyridin-2-yl)benzoic acid | HCID 22736909 | 72,7% |
Reaktionsschritte
In a similar manner to that described in Example 2, a reaction was carried out using methyl 3-trifluoromethylpyridine-6-ylbenzoate (791 mg) and aqueous sodium hydroxide solution (1N, 5.60 ml) and the reaction mixture was treated to afford the title compound (546 mg) which includes some impurity and was used in example 106 without further purification.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06528525B1 |
| Quelldatensatz | uspto-grants-2003_03 |
| ORD ID | ord-c54feab767b34f7c8e3d3a9cfdd867f1 |
| Quellennotiz | uspto-grants-2003_03 |