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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 18650Erstellt: 24. Oktober 2026

Methyl vinyl ketone → 1-{4-[2-(2-Fluoro-phenyl)-5-methyl-pyrrol-1-yl]-benzenesulfonyl}-piperidine

https://huagongshe.com/de/reaction/18650

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktMethyl vinyl ketoneHCID 6570—
Edukto-FluorobenzaldehydeHCID 67970—
Edukt4-(Piperidine-1-sulfonyl)anilineHCID 236648—
Produkt1-{4-[2-(2-Fluoro-phenyl)-5-methyl-pyrrol-1-yl]-benzenesulfonyl}-piperidineHCID 68487442—

Reaktionsschritte

2-Fluorobenzaldehyde and but-3-en-2-one were treated according to the procedure outlined in General Procedure C followed by subjecting the resulting product to conditions outlined in General Procedure D along with p-piperidinylsulfonyl phenylamine to obtain the titled compound. 1H NMR (CDCl3) δ ppm 1.42-1.65 (6H), 2.15 (3H), 2.95 (4H), 6.15 (1H), 6.40 (1H), 6.65-7.90 (8H); MS (ESI) m/z 399 (M+H).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07741364B2
Quelldatensatzuspto-grants-2010_06
ORD IDord-bb2f35b5a8f9432dbf27710baa7497c4
Quellennotizuspto-grants-2010_06