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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 18651Erstellt: 24. Oktober 2026

Sulfanilamide → 4-[2-(2-Fluoro-phenyl)-5-methyl-pyrrol-1-yl]-benzenesulfonamide

https://huagongshe.com/de/reaction/18651

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktSulfanilamideHCID 5333—
EduktMethyl vinyl ketoneHCID 6570—
Edukto-FluorobenzaldehydeHCID 67970—
Produkt4-[2-(2-Fluoro-phenyl)-5-methyl-pyrrol-1-yl]-benzenesulfonamideHCID 68484455—

Reaktionsschritte

2-Fluorobenzaldehyde and but-3-en-2-one were treated according to the procedure outlined in General Procedure C followed by subjecting the resulting product to conditions outlined in General Procedure D along with p-aminosulfonyl phenylamine to obtain the titled compound. 1H NMR (CDCl3) δ ppm 2.18 (3H), 4.71 (2H), 6.13 (1H), 6.34 (1H), 7.05-7.90 (8H); MS (ESI) m/z 331 (M+H).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07741364B2
Quelldatensatzuspto-grants-2010_06
ORD IDord-babaad3c2e6448d8a81dcfd8f4619454
Quellennotizuspto-grants-2010_06