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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 18653Erstellt: 23. Oktober 2026

Methyl vinyl ketone → 1-{4-[2-(3-Chloro-phenyl)-5-methyl-pyrrol-1-yl]-benzenesulfonyl}-piperidine

https://huagongshe.com/de/reaction/18653

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktMethyl vinyl ketoneHCID 6570—
Edukt3-ChlorobenzaldehydeHCID 11477—
Edukt4-(Piperidine-1-sulfonyl)anilineHCID 236648—
Produkt1-{4-[2-(3-Chloro-phenyl)-5-methyl-pyrrol-1-yl]-benzenesulfonyl}-piperidineHCID 68484323—

Reaktionsschritte

3-Chlorobenzaldehyde and but-3-en-2-one were treated according to the procedure outlined in General Procedure C followed by subjecting the resulting product to conditions outlined in General Procedure D along with p-piperidinylsulfonyl phenylamine to obtain the titled compound. 1H NMR (CDCl3) δ ppm 1.42-1.65 (6H), 2.18 (3H), 3.00 (4H), 6.18 (1H), 6.40 (1H), 6.85-7.90 (8H); MS (ESI) m/z 415 (M+H).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07741364B2
Quelldatensatzuspto-grants-2010_06
ORD IDord-2d32fddd135b41969e460b8bf3491573
Quellennotizuspto-grants-2010_06