1-(2-Chloroethyl)piperidine → 1-[(E)-3-(3,4-Dichloro-phenyl)-acryloyl]-4-(2-piperidin-1-yl-ethyl)-[1,4]diazepan-5-one

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	1-(2-Chloroethyl)piperidine	HCID 74827	—
Edukt	1-[(E)-3-(3,4-Dichloro-phenyl)-acryloyl]-[1,4]diazepan-5-one	HCID 62044921	—
Produkt	1-[(E)-3-(3,4-Dichloro-phenyl)-acryloyl]-4-(2-piperidin-1-yl-ethyl)-[1,4]diazepan-5-one	HCID 68432387	—

Reaktionsschritte

In analogy to the procedure described in intermediate 4A, 1-[(E)-3-(3,4-dichloro-phenyl)-acryloyl]-[1,4]diazepan-5-one (intermediate 1A) and 1-(2-chloro-ethyl)-piperidine gave the title compound as white solid. MS: 424.1 (MH+, 2Cl).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07632829B2
Quelldatensatz	uspto-grants-2009_12
ORD ID	ord-2af552448bab4402adb04717ac842f6b
Quellennotiz	uspto-grants-2009_12