HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-(3-Bromopropoxy)tetrahydro-2H-pyran → 1-[(E)-3-(3,4-Dichloro-phenyl)-acryloyl]-4-[3-(tetrahydro-pyran-2-yloxy)-propyl]-[1,4]diazepan-5-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-(3-Bromopropoxy)tetrahydro-2H-pyran | HCID 2777988 | — |
| Edukt | 1-[(E)-3-(3,4-Dichloro-phenyl)-acryloyl]-[1,4]diazepan-5-one | HCID 62044921 | — |
| Produkt | 1-[(E)-3-(3,4-Dichloro-phenyl)-acryloyl]-4-[3-(tetrahydro-pyran-2-yloxy)-propyl]-[1,4]diazepan-5-one | HCID 68435254 | — |
Reaktionsschritte
In analogy to the procedure described in example 5A, 1-[(E)-3-(3,4-dichloro-phenyl)-acryloyl]-[1,4]diazepan-5-one (intermediate 1A]) and 2-(3-bromo-propoxy)-tetrahydro-pyran gave the title compound as white solid. MS: 455.3 (MH+, 2Cl).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07632829B2 |
| Quelldatensatz | uspto-grants-2009_12 |
| ORD ID | ord-dce800a603834be19375384a5461168c |
| Quellennotiz | uspto-grants-2009_12 |