HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
6-(2-Chlorophenyl)-7-(4-chlorophenyl)-3-(cyclohexylmethyl)-[1,2,4]triazolo[4,3-b]pyridazine → 3-Benzyl-6-(2-chlorophenyl)-7-(4-chlorophenyl)-[1,2,4]triazolo[4,3-b]pyridazine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 6-(2-Chlorophenyl)-7-(4-chlorophenyl)-3-(cyclohexylmethyl)-[1,2,4]triazolo[4,3-b]pyridazine | HCID 11993108 | — |
| Edukt | Triphenylphosphane dichloride | HCID 13797396 | — |
| Edukt | N'-(6-(2-chlorophenyl)-5-(4-chlorophenyl)pyridazin-3-yl)-2-phenylacetohydrazide | HCID 57979739 | — |
| Produkt | 3-Benzyl-6-(2-chlorophenyl)-7-(4-chlorophenyl)-[1,2,4]triazolo[4,3-b]pyridazine | HCID 11993109 | 54,6% |
Reaktionsschritte
The title compound (20 mg, 54%) as a white powder was prepared from N′-(6-(2-chlorophenyl)-5-(4-chlorophenyl)pyridazin-3-yl)-2-phenylacetohydrazide (38 mg, 0.085 mmol) and triphenylphosphine dichloride (85 mg, 0.26 mmol) according to the procedures described for 6-(2-chlorophenyl)-7-(4-chlorophenyl)-3-(cyclohexylmethyl)-[1,2,4]triazolo[4,3-b]pyridazine (Example 7B). HPLC/MS (method A): retention time=3.92 min, (M+H)+=431.2.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07632837B2 |
| Quelldatensatz | uspto-grants-2009_12 |
| ORD ID | ord-0de0e1b568fc4027a6c63b2e9479ae13 |
| Quellennotiz | uspto-grants-2009_12 |