Thionyl Chloride → HCID 86629256, Verbindung

HRID 1868691Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1868691
[I:1][C:2]1[C:10]([C:11]([F:14])([F:13])[F:12])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4](O)=[O:5].S(Cl)([Cl:17])=O>>[I:1][C:2]1[C:10]([C:11]([F:14])([F:13])[F:12])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([Cl:17])=[O:5]

Komponenten

3

Edukt 2

HCID 24386Thionyl ChlorideHCID 146125442-Iodo-3-(trifluoromethyl)benzoic acid

Produkt 1

HCID 86629256HCID 86629256, VerbindungAusbeute 99,4 %

Versuchsvorschrift

2-Iodo-3-(trifluoromethyl)benzoic acid (10.0 g, 31.6 mmol) was stirred in thionyl chloride (100 mL, 31.6 mmol) at reflux for 2 hours. The mixture was then cooled to room temperature. The thionyl chloride was removed under vacuum, and the residue was azeotroped with dry toluene to give the product as a yellow-orange semi-solid (10.51 g).

Aufarbeitung

  1. temperatureat reflux for 2 hours
  2. customThe thionyl chloride was removed under vacuum
  3. customthe residue was azeotroped with dry toluene

Quellen und Nachweise

ORD-Eintrag
ord-b6b13cc96d224ffeb2f1caa5ab767cb8
Quelldatensatz
uspto-grants-2009_12
Patentnummer
US07635715B2

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