Phenylhydrazine → (cis)-4-(3-Cyclopentyloxy-4-methoxyphenyl)-2-phenyl-4a,5,8,8a-tetrahydro-2H-phthalazin-1-one
Reaktionsgleichung
[C:1]1([NH:7][NH2:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:9][O:10][C:11]1[CH:12]=[C:13]([C:19]2[C@H:28]3[C@H:23]([CH2:24][CH2:25][CH2:26][CH2:27]3)[C:22](=[O:29])N(CCO)N=2)[CH:14]=[CH:15][C:16]=1[O:17][CH3:18]>>[CH:9]1([O:10][C:11]2[CH:12]=[C:13]([C:19]3[C@H:28]4[C@H:23]([CH2:24][CH:25]=[CH:26][CH2:27]4)[C:22](=[O:29])[N:7]([C:1]4[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=4)[N:8]=3)[CH:14]=[CH:15][C:16]=2[O:17][CH3:18])[CH2:3][CH2:2][CH2:1][CH2:6]1Komponenten
3
Versuchsvorschrift
Prepared from compound E (see starting compounds) and phenylhydrazine as described for compound 35. Crystallization from methanol. M.p. 134°-135° C.
Aufarbeitung
- customCrystallization from methanol