4-Methyloxybenzyl chloride → (cis)-4-(3,4-Dimethoxyphenyl)-2-(4-methoxybenzyl)-4a,5,6,7,8,8a-hexahydro-2H-phthalazin-1-one
Reaktionsgleichung
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:11]2[C@H:20]3[C@H:15]([CH2:16][CH2:17][CH2:18][CH2:19]3)[C:14](=[O:21])[NH:13][N:12]=2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].[CH3:22][O:23][C:24]1[CH:31]=[CH:30][C:27]([CH2:28]Cl)=[CH:26][CH:25]=1.C(N1N=C(C2C=CC(OC)=C(OC)C=2)[C@H]2[C@H](CCCC2)C1=O)C1C=CC=CC=1>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:11]2[C@H:20]3[C@H:15]([CH2:16][CH2:17][CH2:18][CH2:19]3)[C:14](=[O:21])[N:13]([CH2:28][C:27]3[CH:30]=[CH:31][C:24]([O:23][CH3:22])=[CH:25][CH:26]=3)[N:12]=2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10]Komponenten
4
Edukt 3
Produkt 1
Versuchsvorschrift
Prepared from compound 1 and 4-methoxybenzylchloride as described for compound 78. Crystallized from diethyl ether. M.p. 77°-78° C.