(Thian-4-yl)hydrazine → (cis)-4-(3,4-Dimethoxyphenyl)-2-(tetrahydrothiopyran-4-yl)-4a,5,8,8a-tetrahydro-2H-phthalazin-1-one
Reaktionsgleichung
[NH:1]([CH:3]1[CH2:8][CH2:7][S:6][CH2:5][CH2:4]1)[NH2:2].[CH3:9][O:10][C:11]1[CH:12]=[C:13]([C:19]2[C@H:28]3[C@H:23]([CH2:24][CH2:25][CH2:26][CH2:27]3)[C:22](=[O:29])N(CCO)N=2)[CH:14]=[CH:15][C:16]=1[O:17][CH3:18]>>[CH3:9][O:10][C:11]1[CH:12]=[C:13]([C:19]2[C@H:28]3[C@H:23]([CH2:24][CH:25]=[CH:26][CH2:27]3)[C:22](=[O:29])[N:1]([CH:3]3[CH2:8][CH2:7][S:6][CH2:5][CH2:4]3)[N:2]=2)[CH:14]=[CH:15][C:16]=1[O:17][CH3:18]Komponenten
3
Versuchsvorschrift
Prepared from compound C and 4-hydrazinotetrahydrothiopyran as described for compound 35. Crystallized from methanol. M.p. 140°-141° C.
Aufarbeitung
- customCrystallized from methanol