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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1872833Erstellt: 26. Oktober 2026

4-(5-Fluoro-1H-indol-3-YL)cyclohexanone → 3-(4-oxocyclohexyl)-1H-indole-5-carbonitrile

https://huagongshe.com/reaction/1872833

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt4-(5-Fluoro-1H-indol-3-YL)cyclohexanoneHCID 10704683—
Edukt3-(1,4-Dioxa-spiro[4,5]dec-8-yl)-5-cyano-1H-indoleHCID 15521973—
Produkt3-(4-oxocyclohexyl)-1H-indole-5-carbonitrileHCID 11241886—

Reaktionsschritte

This compound was prepared in the manner as described above for (3a) by replacing 4-(5-fluoro-1H-3-indolyl)-cyclohexanone ethylene ketal with 4-(5-cyano-1H-3-indolyl)-cyclohexanone ethylene ketal (6 g) in 81% (4.0 g) of product as a white solid: mp 162.5-164° C.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06110956
Quelldatensatzuspto-grants-2000_08
ORD IDord-2d2af9a4a22843a7bbacec252f6804c3
Quellennotizuspto-grants-2000_08