2-Nitro-5-(3-nitrophenoxy)pyridine → 5-(3-Aminophenoxy)pyridin-2-amine

Beteiligte Stoffe

Reaktionsschritte

To a solution of 2-nitro-5-(3-nitrophenoxy)pyridine (1.33 g, 5.07 mmol) in methanol (10 mL) was added palladium carbon (50% water-containing product, 100 mg), and the mixture was stirred under a hydrogen atmosphere at room temperature for 12 hr. The reaction mixture was filtered through celite, and the filtrate was concentrated under reduced pressure and dried to give the title compound (980 mg, 96%) as a yellow oil.

Herkunft & Nachweise