HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Triethylamine → N-(3-hydroxyphenyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Triethylamine | HCID 8471 | — |
| Edukt | 3-Aminophenol | HCID 11568 | — |
| Edukt | 2,5-Dimethyl-2H-pyrazole-3-carbonyl chloride | HCID 2736299 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | N-(3-hydroxyphenyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide | HCID 19481482 | 90% |
Reaktionsschritte
In the same manner as in Reference Example 11 and using 3-aminophenol (2.11 g, 19.3 mmol), triethylamine (2.81 mL, 20.3 mmol), 1,3-dimethyl-1H-pyrazole-5-carbonyl chloride (3.07 g, 19.4 mmol) and tetrahydrofuran (30 mL) as starting materials, the title compound (4.00 g, 90%) was obtained as a white solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08304557B2 |
| Quelldatensatz | uspto-grants-2012_11 |
| ORD ID | ord-e5a3316baa474928906f4985f5c44ec6 |
| Quellennotiz | uspto-grants-2012_11 |