Hydrogen chloride-ethyl acetate → N-[3-({2-[(cyclopropylcarbonyl)amino]imidazo[1,2-a]pyridin-6-yl}oxy)phenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride

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Reaktionsschritte

To a solution of N-[3-({2-[(cyclopropylcarbonyl)amino]imidazo[1,2-a]pyridin-6-yl}oxy)phenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide (318 mg, 0.739 mmol) in ethanol (15 mL) was added 1N hydrogen chloride-ethyl acetate solution (886 μL), and the mixture was stirred at room temperature for 2 days. The precipitated solid was collected by filtration and washed with ethanol to give the title compound (256 mg, 74%) as a white solid.

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