Cyclopropanecarbonyl chloride → N-[3-({2-[(cyclopropylcarbonyl)amino]imidazo[1,2-a]pyridin-6-yl}oxy)-5-methylphenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide

Beteiligte Stoffe

Reaktionsschritte

In the same manner as in Example 9-2 and using N-{3-[(2-aminoimidazo[1,2-a]pyridin-6-yl)oxy]-5-methylphenyl}-1,3-dimethyl-1H-pyrazole-5-carboxamide (300 mg, 0.797 mmol), cyclopropanecarbonyl chloride (72.0 μL, 0.797 mmol) and N,N-dimethylacetamide (10 mL) as starting materials, the title compound (111 mg, 31%) was obtained as a pale-yellow solid.

Herkunft & Nachweise