HCID 51042485, Verbindung → 3-{4-[5,6-Difluoro-2-(2-hydroxy-pyridin-3-yl)-benzoimidazol-1-ylmethyl]-phenyl}-propionic acid methyl ester
Reaktionsgleichung
C1(CN2C3C=C(F)C(F)=CC=3N=C2C2C(OCC3CCCC3)=NC=CC=2)CCCCC1.[CH3:32][O:33][C:34](=[O:71])[CH2:35][CH2:36][C:37]1[CH:42]=[CH:41][C:40]([CH2:43][N:44]2[C:48]3[CH:49]=[C:50]([F:54])[C:51]([F:53])=[CH:52][C:47]=3[N:46]=[C:45]2[C:55]2[C:56]([O:61]CC3C=CC(OC)=CC=3)=[N:57][CH:58]=[CH:59][CH:60]=2)=[CH:39][CH:38]=1>>[CH3:32][O:33][C:34](=[O:71])[CH2:35][CH2:36][C:37]1[CH:38]=[CH:39][C:40]([CH2:43][N:44]2[C:48]3[CH:49]=[C:50]([F:54])[C:51]([F:53])=[CH:52][C:47]=3[N:46]=[C:45]2[C:55]2[C:56]([OH:61])=[N:57][CH:58]=[CH:59][CH:60]=2)=[CH:41][CH:42]=1Komponenten
3
Edukt 2
Produkt 1
Versuchsvorschrift
The title compound was synthesized in analogy to Example 5, intermediate b, from 3-(4-{5,6-difluoro-2-[2-(4-methoxy-benzyloxy)-pyridin-3-yl]-benzoimidazol-1-ylmethyl}-phenyl)-propionic acid methyl ester. Colorless solid (69%). MS (Turbo Spray): m/z=424.3 (M+H).