Triethylsilane → Ethyl 2-ethyl-5-(1-ethylpropyl)thiophene-3-carboxylate

Beteiligte Stoffe

Reaktionsschritte

To a solution of ethyl 2-ethyl-5-(1-ethyl-1-hydroxypropyl)thiophene-3-carboxylate (3.71 g) synthesized above in trifluoroacetic acid (35 mL) was added triethylsilane (6.61 mL), and the mixture was stirred at room temperature for 2 hr and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (hexane alone) to give the title compound (2.28 g, 65%) as a colorless oil.

Herkunft & Nachweise