Thionyl Chloride → 3-[Chloro(cyclopentyl)methyl]-2-methyl-5-phenylfuran

HRID 1877066Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1877066
[CH:1]1([CH:6]([C:8]2[CH:12]=[C:11]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[O:10][C:9]=2[CH3:19])O)[CH2:5][CH2:4][CH2:3][CH2:2]1.S(Cl)([Cl:22])=O>C1(C)C=CC=CC=1>[Cl:22][CH:6]([CH:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1)[C:8]1[CH:12]=[C:11]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[O:10][C:9]=1[CH3:19]

Komponenten

4

Edukt 2

HCID 24386Thionyl ChlorideHCID 68509772Cyclopentyl(2-methyl-5-phenylfuran-3-yl)methanol

Produkt 1

HCID 685140893-[Chloro(cyclopentyl)methyl]-2-methyl-5-phenylfuranAusbeute 100 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

To a solution of cyclopentyl(2-methyl-5-phenylfuran-3-yl)methanol (0.9 g) in toluene (20 mL) was added thionyl chloride (0.5 mL), and the mixture was stirred at room temperature overnight. The solvent was evaporated under reduced pressure to give the title compound (1.0 g, 100%) as an oil.

Aufarbeitung

  1. customThe solvent was evaporated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-33ed6ed5150244c3820f26b7b43f1c9b
Quelldatensatz
uspto-grants-2012_11
Patentnummer
US08309580B2

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