m-Chlorophenylhydrazine hydrochloride → HCID 58345436, Verbindung

HRID 1877981Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1877981
[CH2:1]([O:3][C:4](=[O:20])[C:5](=O)[CH2:6][C:7]([C:9]1[CH:14]=[CH:13][C:12]([O:15][CH3:16])=[C:11]([O:17][CH3:18])[CH:10]=1)=O)[CH3:2].Cl.[Cl:22][C:23]1[CH:24]=[C:25]([NH:29][NH2:30])[CH:26]=[CH:27][CH:28]=1>>[Cl:22][C:23]1[CH:24]=[C:25]([N:29]2[C:7]([C:9]3[CH:14]=[CH:13][C:12]([O:15][CH3:16])=[C:11]([O:17][CH3:18])[CH:10]=3)=[CH:6][C:5]([C:4]([O:3][CH2:1][CH3:2])=[O:20])=[N:30]2)[CH:26]=[CH:27][CH:28]=1

Komponenten

3

Edukt 2

HCID 75331m-Chlorophenylhydrazine hydrochlorideHCID 43186887Ethyl 4-(3,4-dimethoxyphenyl)-2,4-dioxobutanoate

Produkt 1

HCID 58345436HCID 58345436, VerbindungAusbeute 74 %

Versuchsvorschrift

Starting from 1 g (3.57 mmol) of 4-(3,4-dimethoxyphenyl)-2,4-dioxobutanoic acid ethyl ester from example 12A and 868.8 mg (4.85 mmol) of 3-chlorophenylhydrazine hydrochloride, 1.03 g (2.7 mmol, 74% yield of theory) of product are obtained according to the method described in example 4A and after purification by preparative HPLC.

Aufarbeitung

  1. customare obtained
  2. customafter purification by preparative HPLC

Quellen und Nachweise

ORD-Eintrag
ord-8020358e08c04f1085f73136f4f21512
Quelldatensatz
uspto-grants-2012_11
Patentnummer
US08314089B2

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