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HRID 1878287Erstellt: 27. Oktober 2026

1-(3,5-Dimethylphenyl)piperazine → 1-[(6,7-Dichloro-2-methoxyquinoxalin-3-yl)aminocarbonyl]-4-(3,5-dimethylphenyl)piperazine

https://huagongshe.com/reaction/1878287

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt1-(3,5-Dimethylphenyl)piperazineHCID 2758626—
EduktEthyl N-(6,7-dichloro-2-methoxyquinoxalin-3-yl)carbamateHCID 69243293—
Produkt1-[(6,7-Dichloro-2-methoxyquinoxalin-3-yl)aminocarbonyl]-4-(3,5-dimethylphenyl)piperazineHCID 6924327155%

Reaktionsschritte

Ethyl N-(6,7-dichloro-2-methoxyquinoxalin-3-yl)carbamate and 1-(3,5-dimethyl phenyl)piperazine were reacted by the same way with the example 176 to obtain the titled compound (yield, 55%). 1H NMR (300 MHz, CDCl3) δ 2.30 (s, 6H), 3.16-3.21 (m, 4H), 3.75-3.79 (m, 4H), 4.15 (s, 3H), 6.52-6.59 (m, 3H), 7.31 (br s, 1H), 7.85 (s, 1H), 7.92 (s, 1H).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08314100B2
Quelldatensatzuspto-grants-2012_11
ORD IDord-0357602758154f6d966a6bdaa1108790
Quellennotizuspto-grants-2012_11