3-(Prop-1-en-2-yl)benzaldehyde → HCID 86659734, Verbindung

HRID 1878588Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1878588
[N:1]1([C:7]2[N:12]3[N:13]=[C:14]([C:16]4[CH:21]=[CH:20][N:19]=[CH:18][CH:17]=4)[CH:15]=[C:11]3[N:10]=[C:9]([NH:22][NH2:23])[CH:8]=2)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[C:24]([C:27]1[CH:28]=[C:29]([CH:32]=[CH:33][CH:34]=1)[CH:30]=O)([CH3:26])=[CH2:25]>C(O)C>[C:24]([C:27]1[CH:28]=[C:29]([CH:32]=[CH:33][CH:34]=1)[CH:30]=[N:23][NH:22][C:9]1[CH:8]=[C:7]([N:1]2[CH2:6][CH2:5][O:4][CH2:3][CH2:2]2)[N:12]2[N:13]=[C:14]([C:16]3[CH:17]=[CH:18][N:19]=[CH:20][CH:21]=3)[CH:15]=[C:11]2[N:10]=1)([CH3:26])=[CH2:25]

Komponenten

4

Edukt 2

HCID 197448413-(Prop-1-en-2-yl)benzaldehydeHCID 70867116HCID 70867116, Verbindung

Produkt 1

HCID 86659734HCID 86659734, VerbindungAusbeute 62 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

There was dissolved, in ethanol (2 mL), (7-morpholin-4-yl-2-pyridin-4-yl-pyrazolo[1,5-a]pyrimidin-5-yl)-hydrazine (30.4 mg, 0.0976 mM), then 3-isopropenyl-benzaldehyde (14.3 mg, 0.0976 mM) was added to the solution and the mixture was stirred at room temperature overnight. The reaction liquid was filtered and then the resulting solid was washed with diethyl ether to thus give the title compound (26.6 mg, yield: 62%).

Aufarbeitung

  1. customThe reaction liquid
  2. filtrationwas filtered
  3. washthe resulting solid was washed with diethyl ether

Quellen und Nachweise

ORD-Eintrag
ord-97f3f827e1224f379efb69dce181795c
Quelldatensatz
uspto-grants-2012_11
Patentnummer
US08314098B2

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