Pivalic acid → 1-Methyl-4-nitrosopiperidin-4-yl pivalate

HRID 1879803Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1879803
[CH3:1][N:2]1[CH2:7][CH2:6][C:5](=[N:8][OH:9])[CH2:4][CH2:3]1.C([O-])(=O)C.C([O-])(=O)C.C([O-])(=O)C.C([O-])(=O)C.[Pb+4].[CH3:27][C:28]([CH3:33])([CH3:32])[C:29]([OH:31])=[O:30]>>[C:29]([O:31][C:5]1([N:8]=[O:9])[CH2:6][CH2:7][N:2]([CH3:1])[CH2:3][CH2:4]1)(=[O:30])[C:28]([CH3:33])([CH3:32])[CH3:27]

Komponenten

4

Edukt 3

HCID 6417Pivalic acidHCID 3390531-Methylpiperidin-4-one oximeHCID 178418268HCID 178418268, Verbindung

Produkt 1

HCID 579544641-Methyl-4-nitrosopiperidin-4-yl pivalate

Versuchsvorschrift

1-Methyl-4-nitrosopiperidin-4-yl pivalate was prepared from 1-methyl piperidin-4-one oxime, lead tetraacetate and trimethylacetic acid using conditions of General Method 3. 1H NMR (400 MHz, CHLOROFORM-d) δ 2.86-3.00 (2H, m), 2.37 (3H, s), 2.21-2.35 (4H, m), 1.82-1.94 (2H, m), 1.32 (9H, s).

Quellen und Nachweise

ORD-Eintrag
ord-8e09ce58aef942aa91e359ba1fa6dc7e
Quelldatensatz
uspto-grants-2012_11
Patentnummer
US08318705B2

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