4-Nitrobenzaldehyde → 4-Nitro-alpha-(nitromethyl)benzenemethanol

HRID 1882182

Reaktionsgleichung

Reaktionsgleichung von HRID 1882182
C[SiH2]C1C=CC=CC=1.[N+:9]([C:12]1[CH:19]=[CH:18][C:15]([CH:16]=[O:17])=[CH:14][CH:13]=1)([O-:11])=[O:10].[N+:20]([CH3:23])([O-:22])=[O:21]>C(O)C>[N+:20]([CH2:23][CH:16]([C:15]1[CH:14]=[CH:13][C:12]([N+:9]([O-:11])=[O:10])=[CH:19][CH:18]=1)[OH:17])([O-:22])=[O:21]

Komponenten

5

Edukt 3

HCID 5414-NitrobenzaldehydeHCID 6375NitromethaneHCID 69836Methylphenylsilane

Produkt 1

HCID 108675844-Nitro-alpha-(nitromethyl)benzenemethanol

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

Poly (methylphenylsilane)-supported copper (204 mg, 5 mmol) was added to an ethanol (2.0 ml) solution of p-nitrobenzaldehyde (0.4 mmol) and nitromethane (1.2 mmol), and was stirred at room temperature for 3 hr. The reaction mixture was filtrated, and the filtrate was concentrated, and analyzed by 1H-NMR. Resultantly, 2-nitro-1-(4-nitrophenyl)ethanol was produced at the conversion rate of 95%.

Aufarbeitung

  1. filtrationThe reaction mixture was filtrated
  2. concentrationthe filtrate was concentrated

Quellen und Nachweise

ORD-Eintrag
ord-c093846e91df48c09de4ea3bc7897369
Quelldatensatz
uspto-grants-2012_11
Patentnummer
US08318967B2

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