HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Nitro-3-phenyl-L-alanine → N-(2,6-Dichlorobenzoyl)-4-nitro-L-phenylalanine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Nitro-3-phenyl-L-alanine | HCID 13706 | — |
| Edukt | Sodium Hydroxide | HCID 14798 | — |
| Edukt | 2,6-Dichlorobenzoyl chloride | HCID 78392 | — |
| Lösungsmittel | Acetone | HCID 180 | — |
| Produkt | N-(2,6-Dichlorobenzoyl)-4-nitro-L-phenylalanine | HCID 58018322 | — |
Reaktionsschritte
Concretely, 4-nitro-L-phenylalanine and 2,6-dichlorobenzoylchloride are condensed in a mixed solvent of a sodium hydroxide aqueous solution and acetone with keeping the reaction temperature at 5 to 15° C., and then crystallization is conducted to obtain a corresponding condensed substance, Nα-(2,6-dichlorobenzoyl)-4-nitro-L-phenylalanine almost quantitatively.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08318975B2 |
| Quelldatensatz | uspto-grants-2012_11 |
| ORD ID | ord-7729fd84b55240708f87f0ec4ff3706d |
| Quellennotiz | uspto-grants-2012_11 |