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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1882185Erstellt: 26. Oktober 2026

4-Nitro-3-phenyl-L-alanine → N-(2,6-Dichlorobenzoyl)-4-nitro-L-phenylalanine

https://huagongshe.com/reaction/1882185

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt4-Nitro-3-phenyl-L-alanineHCID 13706—
EduktSodium HydroxideHCID 14798—
Edukt2,6-Dichlorobenzoyl chlorideHCID 78392—
LösungsmittelAcetoneHCID 180—
ProduktN-(2,6-Dichlorobenzoyl)-4-nitro-L-phenylalanineHCID 58018322—

Reaktionsschritte

Concretely, 4-nitro-L-phenylalanine and 2,6-dichlorobenzoylchloride are condensed in a mixed solvent of a sodium hydroxide aqueous solution and acetone with keeping the reaction temperature at 5 to 15° C., and then crystallization is conducted to obtain a corresponding condensed substance, Nα-(2,6-dichlorobenzoyl)-4-nitro-L-phenylalanine almost quantitatively.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08318975B2
Quelldatensatzuspto-grants-2012_11
ORD IDord-7729fd84b55240708f87f0ec4ff3706d
Quellennotizuspto-grants-2012_11