Aniline → HCID 178418952, Verbindung
Reaktionsgleichung
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][C:2]1=[O:10].[N:11]1([CH2:17][CH2:18][CH2:19][NH:20][C:21]2[CH:26]=[CH:25][C:24]([NH2:27])=[CH:23][CH:22]=2)[CH2:16][CH2:15][O:14][CH2:13][CH2:12]1.N[C:29]1C=CC=CC=1>>[N:11]1([CH2:17][CH2:18][CH2:19][NH:20][C:21]2[CH:26]=[CH:25][C:24]([NH:27][CH:29]=[C:3]3[C:4]4[C:9](=[CH:8][CH:7]=[CH:6][CH:5]=4)[NH:1][C:2]3=[O:10])=[CH:23][CH:22]=2)[CH2:16][CH2:15][O:14][CH2:13][CH2:12]1Komponenten
4
Versuchsvorschrift
Example 298-301 are prepared by substituting the appropriate 6′-fluoro or 5′-chloro or 5′-fluoro or 4′-fluoro substituted 1,3-dihydro-indol-2-one for the 1,3-dihydro-indol-2-one and N-(3-morpholin-4-yl-propyl)-benzene-1,4-diamine (used in the preparation of Example 297) for aniline in the reaction of Example 1.
Aufarbeitung
- customExample 298-301 are prepared
- customin the reaction of Example 1