Methylhydrazine → HCID 59394553, Verbindung
Reaktionsgleichung
[CH3:1][C:2]1([C:5](=O)[CH2:6][C:7]#[N:8])[CH2:4][CH2:3]1.[CH3:10][NH:11][NH2:12]>CO>[CH3:10][N:11]1[C:7]([NH2:8])=[CH:6][C:5]([C:2]2([CH3:1])[CH2:4][CH2:3]2)=[N:12]1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
A solution of 3-(1-methyl-cyclopropyl)-3-oxo-propionitrile (1.0 g, 8.1 mmol), methylhydrazine (0.56 g, 12.2 mmol) and MeOH (40 mL) is heated at 80° C. for 16 h. The solution is then concentrated in vacuo and the residue is suspended in 5 mL DCM and 20 mL heptane, filtered to give product. MS (ESI) m/z 152.3 (M+1).
Aufarbeitung
- concentrationThe solution is then concentrated in vacuo
- filtration20 mL heptane, filtered
- customto give product
Quellen und Nachweise
- ORD-Eintrag
- ord-f07a3b9643484edab356bbe87725c8a1
- Quelldatensatz
- uspto-grants-2013_08
- Patentnummer
- US08501756B2
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