Hydrochloric Acid → HCID 68412886, Verbindung
Reaktionsgleichung
[NH2:1][C:2]([CH3:45])([CH3:44])[C:3]([NH:5][C@H:6]([CH2:33][C:34]1[C:42]2[C:37](=[CH:38][CH:39]=[CH:40][CH:41]=2)[N:36]([CH3:43])[CH:35]=1)[C:7](=[O:32])[NH:8][CH:9]1[CH2:18][C:17]2[C:12](=[C:13]([N:19]3[CH2:23][CH2:22][CH2:21][C:20]3=[O:24])[CH:14]=[CH:15][CH:16]=2)[N:11]([CH2:25][C:26]2[CH:30]=[CH:29][S:28][CH:27]=2)[C:10]1=[O:31])=[O:4].[ClH:46]>C(O)C>[ClH:46].[NH2:1][C:2]([CH3:45])([CH3:44])[C:3]([NH:5][C@H:6]([CH2:33][C:34]1[C:42]2[C:37](=[CH:38][CH:39]=[CH:40][CH:41]=2)[N:36]([CH3:43])[CH:35]=1)[C:7](=[O:32])[NH:8][CH:9]1[CH2:18][C:17]2[C:12](=[C:13]([N:19]3[CH2:23][CH2:22][CH2:21][C:20]3=[O:24])[CH:14]=[CH:15][CH:16]=2)[N:11]([CH2:25][C:26]2[CH:30]=[CH:29][S:28][CH:27]=2)[C:10]1=[O:31])=[O:4]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
2-Amino-2-methyl-N-[(2R)-3-(1-methyl-1H-indol-3-yl)-1-oxo-1-[2-oxo-8-(2-oxopyrrolidin-1-yl)-1-(thiophen-3-ylmethyl)-1,2,3,4-tetrahydroquinolin-3-ylamino]propan-2-yl]propanamide (116 mg) was dissolved in ethanol (1.0 mL), and 1N hydrochloric acid (161 μL) was added thereto. Subsequently, the solvent was evaporated under reduced pressure, whereby the title compound (103 mg) was yielded.