3-(aminomethyl)-7-chloro-1-phenylquinolin-4(1H)-one → HCID 71217342, Verbindung
Reaktionsgleichung
[NH2:1][CH2:2][C:3]1[C:12](=[O:13])[C:11]2[C:6](=[CH:7][C:8]([Cl:14])=[CH:9][CH:10]=2)[N:5]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:4]=1.[Cl:21][C:22]1[CH:38]=[CH:37][C:25]([CH2:26][N:27]2[CH:32]=[CH:31][C:30]([C:33](O)=[O:34])=[CH:29][C:28]2=[O:36])=[CH:24][CH:23]=1>>[Cl:14][C:8]1[CH:7]=[C:6]2[C:11]([C:12](=[O:13])[C:3]([CH2:2][NH:1][C:33]([C:30]3[CH:31]=[CH:32][N:27]([CH2:26][C:25]4[CH:24]=[CH:23][C:22]([Cl:21])=[CH:38][CH:37]=4)[C:28](=[O:36])[CH:29]=3)=[O:34])=[CH:4][N:5]2[C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=2)=[CH:10][CH:9]=1Komponenten
3
Versuchsvorschrift
1-(4-Chloro-benzyl)-2-oxo-1,2-dihydro-pyridine-4-carboxylic acid (7-chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-amide was prepared starting from intermediate D and 1-(4-chlorobenzyl)-2-oxo-1,2-dihydropyridine-4-carboxylic acid. MS calcd. for C29H21Cl2N3O3 [(M+H)+] 530.1, obsd. 530.0.
Quellen und Nachweise
- ORD-Eintrag
- ord-a77f013fa2a34d69a2633b6197e4fd6e
- Quelldatensatz
- uspto-grants-2013_08