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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1888270Erstellt: 26. Oktober 2026

Triethylamine → HCID 178477702, Verbindung

https://huagongshe.com/reaction/1888270

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktTriethylamineHCID 8471—
EduktEthanesulfonyl chlorideHCID 11667—
EduktHCID 178479542HCID 178479542—
LösungsmittelDichloromethaneHCID 6344—
ProduktHCID 178477702HCID 178477702—

Reaktionsschritte

This compound was prepared in a fashion analogous to the procedure described in Example 3. Thus, 3-(4-piperidinyl)-5-(3-thienyl)-1H-indazole-7-carboxamide hydrochloride (Intermediate 19) (0.117 mmol) was reacted with ethane sulfonyl chloride (0.02 mL, 0.234 mmol) in the presence of triethylamine (0.04 mL, 0.468 mmol) in methylene chloride (10 mL) to give the title compound (9.4 mg, 19% for the last two steps)

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08501780B2
Quelldatensatzuspto-grants-2013_08
ORD IDord-8d288bc1b3644834885618bae5388d28
Quellennotizuspto-grants-2013_08