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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1888277Erstellt: 26. Oktober 2026

Triethylamine → HCID 178477699, Verbindung

https://huagongshe.com/reaction/1888277

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktTriethylamineHCID 8471—
EduktEthanesulfonyl chlorideHCID 11667—
EduktHCID 178479540HCID 178479540—
LösungsmittelDichloromethaneHCID 6344—
ProduktHCID 178477699HCID 178477699—

Reaktionsschritte

This compound was prepared in a fashion analogous to the procedure described in Example 3. Thus 3-(4-piperidinyl)-5-(3-pyridinyl)-1H-indazole-7-carboxamide hydrochloride (Intermediate 21) (0.09 mmol) was reacted with ethane sulfonyl chloride (0.01 mL, 0.217 mmol) in the presence of triethylamine (0.04 mL, 0.468 mmol) in methylene chloride (10 mL) to give the title compound (4.9 mg, 13% for the last two steps)

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08501780B2
Quelldatensatzuspto-grants-2013_08
ORD IDord-06aebaefeaeb4ed088fcd0e4819e3401
Quellennotizuspto-grants-2013_08